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Metronidazole is actually a nitroimidazole and may be made use of with treatment in clients with evidence of, or history of blood dyscrasia.
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Oral metronidazole has long been noted to potentiate the anticoagulant outcome of coumarin and warfarin, leading to a prolongation of prothrombin time. Use warning when prescribing for patients who're getting anticoagulant therapy.
There has been no working experience thus far with using METROGEL-VAGINAL in pregnant sufferers. Metronidazole crosses the placental barrier and enters the fetal situs jnetogel circulation rapidly. No fetotoxicity or teratogenicity was observed when metronidazole was administered orally to pregnant mice at six periods the suggested human dose (based upon mg/m2); nevertheless, in an individual small research wherever the drug was administered intraperitoneally, some intrauterine deaths were being observed. The relationship of those results into the drug is unknown.
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